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Ceramide

Product Name
Ceramide
CAS No.
104404-17-3
Chemical Name
Ceramide
Synonyms
CERAMIDE;CERAMIDE;CERAMIDE;CERAMIDE;CERAMIDE;N-oleoylsphingosine;Ceramide (d18:1/16:0);Ceramide (d18:1/12:0);Ceramide (d18:1/18:0);Ceramide (d18:1/20:0)
CBNumber
CB8764212
Molecular Formula
C34H66NO3R
Formula Weight
536.89
MOL File
104404-17-3.mol
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Ceramide Property

InChIKey
XJRPTDNTEPSGLZ-UHFFFAOYSA-N
SMILES
C(OC(C)=O)(C(CCCCCCCCCCCCCC)OC(C)=O)C(CO)NC(CCCCCCCCCCCCCCCCCCCCCCCCC)=O
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
LIP0004196
Product name
CERAMIDE
Purity
95.00%
Packaging
5MG
Price
$755.06
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
LIP0004196
Product name
CERAMIDE
Purity
95.00%
Packaging
25MG
Price
$1190.07
Updated
2021/12/16
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Ceramide Chemical Properties,Usage,Production

Definition

ChEBI: N-octadecanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as octadecanoyl (stearoyl). It has a role as a mouse metabolite. It is a N-acylsphingosine and a N-stearoyl-sphingoid base. It is functionally related to an octadecanoic acid.

benefits

Ceramides are lipids, which are fatty acids that are produced in the sebaceous glands. Ceramides help to moisturise and strengthen the protective skin moisture barrier, and protect the skin from external aggressors such as weather and pollution.

Mode of action

Topically applied ceramide (Cer) could improve barrier function in three possible ways: (1) Cer in an appropriate formulation constructs (lamellar) liquid crystalline and/or gel structures; (2) Cer is likely incorporated into lamellar bilayer structures in the SC to repair incompetent bilayer structures; and/or (3) Cer penetrates into nucleated layers of the epidermis and becomes a precursor to endogenous Cer synthesis following hydrolysis to the sphingoid base and FA. In addition, Cer absorbed into nucleated layers of the epidermis could suppress KC proliferation and promote differentiation. Because Cer production is increased during KC differentiation, the stimulation of KC differentiation can increase de novo Cer production, thereby contributing to barrier formation[1].

References

[1] Kyong-Oh Shin. “Exogenous Ceramide Serves as a Precursor to Endogenous Ceramide Synthesis and as a Modulator of Keratinocyte Differentiation.” Cells (2022).

Ceramide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ceramide manufacturers

Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
CERAMIDE NS/CERAMIDE NG 104404-17-3
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
99%
Supply Ability
2000kgs
Release date
2023-12-18
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Ceramide 104404-17-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-05-08
BINBO BIOLOGICAL CO.,LTD
Product
Ceramide 104404-17-3
Price
US $0.00/kg
Min. Order
1kg
Purity
10%
Supply Ability
1000 kg
Release date
2024-04-08

104404-17-3, CeramideRelated Search:


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